Resolving Chronic Pain _ The Scientist

نویسندگان

  • Claudia Sommer
  • Frank Birklein
چکیده

Inflammation is correctly blamed as one of the root causes of both acute and chronic pain—and more. Not only does chronic inflammation underlie disorders such as rheumatoid arthritis, inflammatory bowel disease, and other autoimmune diseases, it has also been implicated in the pathogenesis of cancer, chronic heart failure, and neurological disorders such as Parkinson’s and Alzheimer’s diseases. These conditions affect millions, and carry high health-care and socioeconomic costs. And yet, inflammation is an important physiological response that jump-starts tissue repair and more carefully tunes immune reactions. Without it, we could not fight off infection or heal from injury. Why and how does this powerful ally turn into a foe?

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

تأثیر روش درمان گروهی مرور زندگی در سالمندان مبتلا به درد مزمن

Objectives: Chronic pain is a common problem in the elderly. The prevalence of pain indicates that among the Iranian older population who are living in nursing homes, at any specific time, at least 72.8% experience pain. Research designed as a structured review of one’s life is helpful, even is therapeutic in elderly. The aim of life review therapy increases life satisfaction, improves se...

متن کامل

The Impact of Pain on Different Aspects of Life Among Older People With Chronic Pain

Objectives: This study aimed to investe the impact of pain on older people with chronic pain. Methods & Materials: Participants were 585 individuals (n=77 aged 60 years andover, n=508 aged Lessthan 60 years old) with chronic pain in their leg, back, hands, neck and shoulders. The main assessment measure was the West Haven-Yale Multidimensional Pain Inventory (WHYMPI). Results: The two gro...

متن کامل

Divergent roles of immune cells and their mediators in pain

Chronic pain is a major debilitating condition that is difficult to treat. Although chronic pain may appear to be a disorder of the nervous system, crucial roles for immune cells and their mediators have been identified as important contributors in various types of pain. This review focuses on how the immune system regulates pain and discusses the emerging roles of immune cells in the initiatio...

متن کامل

Defining chronic pain ethics.

OBJECTIVE To identify current issues in the diagnosis and treatment of chronic pain. DESIGN Focus groups were convened to discuss the current issues in chronic pain care. Commentary was analyzed across focus groups using an interpretivist method of qualitative data analysis. Setting.  Focus groups were held in five major US cities throughout the United States. PARTICIPANTS Key stakeholders ...

متن کامل

The role of self-efficacy, pain catastrophizing, and fear of movement on chronic pain adjustment of rheumatoid arthritis patients

 Aims and background: People respond to chronic pain in various ways and pain adjustment is not the same in different individuals. The aim of the current study is the assessment of the level of chronic pain adjustment in rheumatoid arthritis (RA) patients based on the quality of life, physical disability, and the level of their depression. In addition, the role of three variables, pain catas...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012